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Bromelain enzyme is a mercaptohydrolase from pineapple, which is a food-grade enzyme produced by modern biotechnology with refining, purifying, concentration, and drying. Its molecular weight is 33 000 and isoelectric point is 9.55. The active center of bromelain is sulfhydryl (-SH). It mainly comes from plant stem, so it is also called stem bromelain. The main component is a mercaptohydrolase and it also contains non-proteolytic enzymes, including peroxidase, acid phosphatase, amylase, and cellulase. It is widely used in food processing (such as the meat processing industry, baking enzymes, and etc.), medicine, and biology industries for the capability of hydrolyzing various proteins.
(CAS Number: 9001-00-7)
|Physical Appearance||White to light yellow powder|
|Activity||300,000 U/g；500,000 U/g； 800,000 U/g；1,200,000 U/g|
Fig.1 pH Curve
Fig.2 Temperature curve
Mg2+ and Ca2+ can inhibit bromelain activity at high concentration, while they can promote bromelain activity at low concentration.
- Food industry
Bromelain is a natural, non-toxic, and non-side-effect protein. It has a remarkable effect on protein hydrolysis for the extensive enzymes contained.
It can be used for meat tenderization, the production of bioactive peptides, hydrolyzed gelatin, soybean protein concentrate, clarified beer, fish sauce, and fermented soybean milk.
- Medical area
It has been proved as a safe and effective therapeutic drug.
The effect on the prevention and treatment of diarrhea in piglets is quite good for the protein hydrolysis function by inhibiting the receptor activity of enterotoxigenic Escherichia coli in the animal intestine, so as to reduce the adhesion to the intestine.
In the field of medicine, it can prevent platelet aggregation, fibrinolysis, anti-inflammatory, anti-tumor, cytokines and immune regulation, skin debridement, promote the absorption of other drugs, mucolysis, help digestion, promote wound healing, improve the cardiovascular and circulatory system.
Stored under 10℃ in the original sealed package, the activity of solid enzyme remains stable for a period of up to 12months; the shelf life can be prolonged if stored at -5℃.
This product is a non-toxic, but long time contact may irritate the skin and eyes. The dust may cause sensitization when inhaled. Please take precautions to avoid direct contact with the product. Rinsing thoroughly with a copious amount of warm water with soap in case of contact with the skin, seek medical advice if lung irritation occurs. During the operation, a gauze mask and eyeshade is suggested to wear.
More About Bromelain
Application in the Food Processing Industry
- Bakery Products: adding Bromelain into the dough can make the gluten degradation and the dough is softened and easy to process. It can also improve the taste and quality of biscuits and bread.
- Cheese: it can be used for the condensation of casein.
- Meat tenderization: bromelain can hydrolyze the large molecule protein of meat protein into small molecule amino acid and protein that can be easily absorbed. . The enzyme can be widely used in the finishing of meat products.
- The application of bromelain in other food processing industries:
· Some people have used bromelain to increase the PDI value of soybean cake and soybean meal. and NSI values to produce soluble protein products and breakfast, cereal and beverages containing soy flour.
· Others include the production of dehydrated pulses, baby food, and margarine; clarification of apple juice; manufacture of fudge; and digestible food for patients; add flavor to daily food, etc.
Application in Medical and Health Care Industry
- Inhibit the Growth of Tumor Cells
It has been observed in relevant clinical studies that Bromelain can inhibit the growth of tumor cells.
- The prevention and control of cardiovascular disease
Bromelain is beneficial as a protein hydrolase in the prevention of cardiovascular disease. It inhibits heart attacks and strokes caused by platelet aggregation, relieves angina symptoms, moderates arterial constriction, accelerates fibrinogen The decomposition.
- It is used for scabbing off burns.
Bromelain selectively removes the skin, allowing early neo-skin grafting to take place. Bromelain has been shown to have no adverse effects on adjacent normal skin in animal studies. The use of topical antibiotics does not affect the effect of bromelain.
It is effective in treating inflammation and edema in a variety of tissues (including thrombophlebitis, skeletal muscle injuries, hematomas, stomatitis). It has the potential to activate the inflammatory response (e.g., diabetic ulcers and sports injuries). It can also treat diarrhea.
- Improve drug absorption
Combining with various antibiotics (e.g., tetracycline, amoxicillin, etc.) enhances its therapeutic efficacy. Studies have shown that it promotes the transmission of antibiotics to the site of infection, thereby reducing the need for antibiotics. Presumably, it has a similar effect on anti-cancer drugs. In addition, it can promote the absorption of nutrients.
Application in the Cosmetic Industry
Bromelain has the excellent effect of skin rejuvenation, whitening, and spot removal.
The basic principle of action: It can act on the aging keratin layer of the human skin, prompting its degradation, decomposition, removal, and promote the development of the skin. Skin metabolism, reducing the darkening of the skin caused by sun exposure. Make skin maintenance presents a good white state.
Application in Animal Feed
Adding Bromelain to feed formulations or mixing it directly into feed can greatly increase protein utilization and conversion, and can Develop a wider range of protein sources, thereby reducing feed costs.